The extract of ginkgo (Ginkgo biloba) could not be effective in preventing or slowing dementia associated with aging, according to a recent study published in the Journal of the American Medical Association (JAMA). The clinical trial was conducted in the United States to 3 069 people aged on average 79 years.
Participants were initially sound mind (2 587 subjects) or distressed slight cognitive deficits associated with age (482 subjects). During six to seven years, they had to take two tablets a day of a standardized extract of ginkgo (120 mg per tablet extract - EGB 761 ®) or a placebo equivalent. At the end of the test, about 3% of the participants had received a medical diagnosis of dementia or Alzheimer's disease and the proportion of people living in the same was assigned to the ginkgo group and the control group.
The study noted that it is possible that ginkgo may be beneficial in the long term in people aged less, but they do not hide their disappointment at the results.
In this test, the researchers did not compare the effects of ginkgo to a drug, since there is still no evidence that has any effectiveness in this regard. They were looking at whether ginkgo could fill this vacuum therapy.
"The time between the initial changes in the brain and the onset of clinical signs of dementia is very long, so it is always possible that ginkgo has effects, positive or negative, over a period of time long, "write the authors of the study concluded.
Only 60% of the participants had taken their tablets accurately, both in the placebo group than in the active group, also reported the researchers. It is unclear if this protocol glitch could affect the results.
Researchers have however found no adverse effects related to ginkgo, including the risks of bleeding that often associated with the use of this plant. Further tests on the scale of ginkgo are underway.
Participants were initially sound mind (2 587 subjects) or distressed slight cognitive deficits associated with age (482 subjects). During six to seven years, they had to take two tablets a day of a standardized extract of ginkgo (120 mg per tablet extract - EGB 761 ®) or a placebo equivalent. At the end of the test, about 3% of the participants had received a medical diagnosis of dementia or Alzheimer's disease and the proportion of people living in the same was assigned to the ginkgo group and the control group.
The study noted that it is possible that ginkgo may be beneficial in the long term in people aged less, but they do not hide their disappointment at the results.
In this test, the researchers did not compare the effects of ginkgo to a drug, since there is still no evidence that has any effectiveness in this regard. They were looking at whether ginkgo could fill this vacuum therapy.
"The time between the initial changes in the brain and the onset of clinical signs of dementia is very long, so it is always possible that ginkgo has effects, positive or negative, over a period of time long, "write the authors of the study concluded.
Only 60% of the participants had taken their tablets accurately, both in the placebo group than in the active group, also reported the researchers. It is unclear if this protocol glitch could affect the results.
Researchers have however found no adverse effects related to ginkgo, including the risks of bleeding that often associated with the use of this plant. Further tests on the scale of ginkgo are underway.
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