The fast-dood, which is rich in sugar, fat and cholesterol, promotes the development of Alzheimer's disease, according to a doctoral thesis at the Karolinska Institute in Sweden.
Mice that received for nine months a diet rich in fat, sugar and cholesterol have developed brain abnormalities similar to those found in people with Alzheimer's disease.
The researcher is Susanne Akterin his colleagues found in mice modified génétiquememt, an increase of phosphate attached to the tau proteins that accumulate inside the nerve cells and prevents them from functioning normally. Cholesterol also reduced levels of another substance, the Arc protein involved in the encoding of memory.
These mice had first been genetically modified to mimic the effect of a variant of a human gene called apoE4, which is a risk factor for the disease and one of whose functions is to transport cholesterol.
A high intake in fat and cholesterol, combined with genetic factors, may affect several substances in the brain and be one of the causes of developing Alzheimer's disease, summarized the researcher.
Previous research has shown that a relatively low dietary antioxidants may also increase the risk of Alzheimer's. This research has shown that two antioxidants are dysfunctional in the brains of people with Alzheimer's disease, which can lead to the death of nerve cells.
Mice that received for nine months a diet rich in fat, sugar and cholesterol have developed brain abnormalities similar to those found in people with Alzheimer's disease.
The researcher is Susanne Akterin his colleagues found in mice modified génétiquememt, an increase of phosphate attached to the tau proteins that accumulate inside the nerve cells and prevents them from functioning normally. Cholesterol also reduced levels of another substance, the Arc protein involved in the encoding of memory.
These mice had first been genetically modified to mimic the effect of a variant of a human gene called apoE4, which is a risk factor for the disease and one of whose functions is to transport cholesterol.
A high intake in fat and cholesterol, combined with genetic factors, may affect several substances in the brain and be one of the causes of developing Alzheimer's disease, summarized the researcher.
Previous research has shown that a relatively low dietary antioxidants may also increase the risk of Alzheimer's. This research has shown that two antioxidants are dysfunctional in the brains of people with Alzheimer's disease, which can lead to the death of nerve cells.
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